Willow bark has a long history of traditional use for reducing minor pain. Several randomized human trials illustrate its ability to do so primarily through the actions of salicin, a source of salicylic acid. Additionally, it helps to maintain healthy prostaglandin metabolism and blood flow. Boswellia serrata has also revealed the potential to provide statistically significant support for reducing mild pain. AKBA, or 3-acetyl-11-keto-beta-boswellic acid, may be particularly supportive in maintaining healthy 5-lipoxygenase enzyme activity and leukotriene metabolism to maintain tissue comfort. Curcumin maintains healthy cyclooxygenase-2 enzyme activity while supporting healthy prostaglandin, leukotriene and thromboxane metabolism. Devils claw promotes both healthy cyclooxygenase-2 and 5-lipoxygenase enzyme activity. A review of 12 human studies indicates that devils claw may reduce mild pain to promote musculoskeletal comfort and function. dl-Phenylalanine supports enkephalin activity, which impacts pain receptive neurons.*

This formula is designed to reduce occasional, minor pain by supporting healthy enzyme and immune mediator activities.*

Take 2 capsules, 1-3 times daily, with meals.

Serving Size: two vegetarian capsules

Amount Per Serving
White willow extract ... 535mg
(salix alba) (bark)
(standardized to contain 15% salicin)
Indian frankincense extract ... 200mg
(boswellia serrata) (gum resin)
(standardized to contain 70% boswellic acids)
5–LOXIN® Boswellia serrata extract Indian frankincense extract ... 25mg
(boswellia serrata) (gum resin)
(standardized to contain 30% 3-acetyl-11-keto-beta-boswellic acid (AKBA)
Turmeric extract ... 100mg
(curcuma longa) (root)
(standardized to contain 95% curcuminoids)
Devil’s claw extract ... 300mg
(Harpagophytum procumbens and Harpagophytum zeyheri) (root)
(standardized to contain 5% harpagosides)
DL-phenylalanine ... 535mg
(free-form)

Other Ingredients: vegetarian capsule (cellulose, water), ascorbyl palmitate

5-LOXIN®is a registered trademark of PL Thomas – Laila Nutra, LLC and is used under license. International Patents Pending.

Warning: This product contains salicylates. Do not take if allergic to aspirin. Do not combine with aspirin or other products containing salicylates. Not to be used by pregnant or lactating women. Not to be used by children (ages 18 and under). Do not take with anticoagulant or antiplatelet drugs. If you have any health condition, particularly stomach problems or ulcers, or are taking any other medications, consult your health professional before use.

PHENYLKETONURICS: CONTAINS PHENYLALANINE